Research
NACHO is a clinical trials group that can rapidly design and implement pilot translational research and clinical research initiatives. While many other initiatives will be developed and executed in the future, the collaboration is being launched with the implementation of high-impact clinical trials, complimented by companion biology studies to facilitate prospective collection of biological samples.
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The LCH-IV is an international, multi-center, prospective clinical study for pediatric Langerhans cell histiocytosis.
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The LCH-CLO is a phase II study of Clofarabine in patients with recurrent or refractory Langerhans cell histiocytosis.
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The NACHO-COBI is a limited-site study of Cobimetinib in pediatric, young adult, and adult LCH patients with recurrent active disease and histiocytic disorders.
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Publications
NACHO aims to share knowledge learned through the consortium's collaborative efforts by publishing results in scientific journals.