Publications

Support from St. Baldrick’s for the NACHO Consortium is noted in review articles authored by NACHO members discussing progress in LCH research and future directions:

• Allen CE, Merad M and Berres ML (2014).  Progress in understanding pathogenesis of Langerhans cell histiocytosis: Back to Histiocytosis X?  Br J Haematol.  2015 Apr;169(1):3-13.
• Allen CE, Ladisch S, McClain KL. How I Treat LCH.  Blood. 2015 Jul 2;126(1):26-3.

Publications by the research team that will inform future correlative biology studies include:

• Simko SJ, Garmezy B, Abhyankar HA, Lupo P, Chakraborty R, Lim KPHL, Shih A, Hicks MJ, Wright TS, Levy ML, McClain KL and Allen CE (2014). Differentiating Skin-Limited and Multisystem Langerhans Cell Histiocytosis.  Journal of Pediatrics. 165(5):990-6. 
• Chakraborty R, Hampton OA, Shen X, Simko SJ, Shih A, Abhyankar A, Lim KPH, Covington K, Trevino L, Dewal N, Muzny DM, Doddapaneni H, Hu J, Wang L, Lupo PJ, Hicks MJ, Bonilla DL, Dwyer KC,  Berres ML, Poulikakos PI, Merad M, McClain KL, Wheeler DA, Allen CE, Parsons DW. Mutually Exclusive Recurrent Somatic Mutations in MAP2K1 and BRAF Support a Central Role for ERK Activation in LCH Pathogenesis.  Blood. 6;124(19):3007-15. 
• Ribeiro KB, Degar B, Antoneli CB, Rollins B, Rodriguez-Galindo C.  Ethnicity, race and socioeconomic status influence incidence of LCH.  Ped Blood Cancer. Jan 13 2015 epub.